Mirtazapine for Major Depressive Disorder User Reviews (Page 5)

• fattyb
• October 18, 2016

"9 months ago I was prescribed this in combination with venlafaxine to treat major depressive disorder, anxiety and complex ptsd. Initially I did not notice any side effects but about 3 months in I suddenly gained so much weight that none of my clothes fit. It seemed to almost happen overnight and whilst I was struggling with the fact that I had NOTHING to wear, I started to get hot flushes, pee my pants without realising and sweat like a sauna at random moments, esp in my groin area. Lovely. Add to that - memory loss, freaky (exhausting) dreams, fingernails that split if you look at them and trembling hands .....what do you get? A fat sweaty smelly trembly LUMP who is now too depressed and anxious to even go out the front door. I quit."

• Not
• Taken for 6 months to 1 year
• December 2, 2020

Remeron (mirtazapine) "I took Remeron for 6 months, it did wonders for my depression and anxiety during the first weeks, I started with the 15mg dose, but as time passed, the effect started to disappear, I increased my dose to 30, the same thing happened, the effect disappeared, now I am taking 45mg, and the effect is not at all the same as I felt in the first weeks, unfortunately this medicine is not a long-term medicine, I am thinking of changing"

• M J
• Taken for 1 to 6 months
• October 25, 2020

"This is the first review I have submitted. I’m doing so to save someone from the bad experience I had from this drug, mirtazapine. Was prescribed this to help with anxiety, depression and sleep. The first night I slept quite well, but things became steadily worse after that. It gave me a sort of sleep paralysis where I would wake up but not able to move my body. Also have me tremors, restless legs and pains in my joints. The doctor suggested to increase the dose, which made things worse still. So after 6 weeks of hell, I came off it and switched medications. It took another few months for the withdrawal effects to stop (muscle twitches etc...). It may be perfect for some, but this was not a good match for me."

• loulou
• Taken for 1 to 6 months
• January 12, 2016

"This medication is brilliant. After trying various other antideppressants for depression over the last few years with no success and worsening of symptoms, I was giving up hope of ever getting better. Sleep has improved, appetite has increased but after the first month the sugar cravings have subsided. I have put on about 5lbs but its a small price to pay to finally reach the light at the end of the tunnel! I am genuinely happy for the first time in a long long time. There were some side effects at first which subsided after a few weeks, fuzzy head, sleeping too much, massive appetite, dry mouth; all of which have subsided. Started on a 15mg dose and now on 30mg as the lower dose made me drowsy through the day."

• Yanni
• Taken for less than 1 month
• April 8, 2020

"I took this medication mirtazapine for about a week for major depressive disorder. It made me EXTREMELY tired and foggy. I could barely do anything except sleep the entire time I was on it. The doctor said it would pass but I couldn't wait for that to happen because I had to have the energy to go to work every day."

• Weasel
• Taken for less than 1 month
• August 5, 2020

"I started this mirtazapine medicine primarily for depression, which is so bad at the moment. I only stayed on it for about 7 days. The reasons were that it interfered with my DHC (opioid pain reliever) and thus I awoke every morning in far more pain than usual. I also read about bad nightmares with this medicine but until about day 6 never experienced them, however on the sixth evening of taking them I had the most incredibly real and horrifying nightmare I have ever had. I could not turn out the light for a long time, I also had some mild open eye sort of hallucinations too like seeing lights moving around my bedroom. And finally the constant feelings of being really tired and exhausted all the time. It did give take a little edge of the extreme feelings but I was just too dopey all the time. I believe this medicine could help some people but not for me."

• Bubzz...
• May 20, 2016

"Post update from 3 weeks ago, im now 4 weeks in on 30mg but have decided to taper off due to the weight gain and dizziness. I'm now 203lbs after gaining another 8 pounds from increasing to 30mg from 15mg. In a total of 10 weeks from starting this medication from 7.5mg i gained 20 pounds and 3 inches on my waist. The side effects unfortunately out weigh the benefits. This medication just makes you want to eat anything in sight. I feel like a fat blob where 10 weeks ago i was somewhat fit. I can't control the carb and sugar cravings. Onto the next med i guess!"

• Lilmi...
• Taken for 1 to 6 months
• January 7, 2022

Remeron (mirtazapine) "This medicine completely wipes me out. All it does is makes me sleep. I can sleep over 24 hours straight when I take this. Does nothing for depression because it makes me sleepy and can’t do anything anyways when you’re sleepy."

• Becks
• July 31, 2017

"I had been on quite a few SSRIs and nothing helped my Major Depression and Panic Disorder. This was a last route medication for me and ended up working like a dream. I was eased onto the meds slowly which helped my doctor determine the correct dosage once I got used to it. I have experienced weight gain but the weight gain does not increase with the dosage. Also, I've had some acne flare ups. I take the medicine at night so the drowsiness doesn't ruin my day. The side effects are a small price to pay for the exchange of a happy life again! ****If you have had trouble with Prozac, Zoloft, etc. please ask your doctor to try this medication next! I wish I had found this years earlier!****"

• Amy...
• October 13, 2017

"Vile absolutely vile and addictive if your struggling in life and have an addictive personality as they make you sleep and give you some relief. The need to eat is intense. Please don't drink with them you will black out and not remember a thing. Take with caution Much love keep strong. Xxxxxxxx"

• Han
• Taken for 1 to 6 months
• February 26, 2021

"I’ve been dealing with chronic depression my whole life with terrible anxiety. Tried all kinds of anti-depressants over the years and this drug is a GOD SENT. I’ve never liked most antidepressants due to the negative effects on sex drive and this hasn’t messed with my sex life one bit. Made me extremely groggy/sluggish with crazy hunger at first but after a month or two of taking it all bad side effects went away. Doesn’t make me feel like an emotionless zombie like most other antidepressants. Went from having panic attacks every day to one every two weeks MAYBE. I’m the happiest I’ve been in years. Only been taking it for about 4/5 months as well."

• Roxanne
• Taken for 6 months to 1 year
• January 11, 2022

"I have been taking mirtazapine for 8 months of 15mg. I had major depression with anxiety panic attacks and insomnia.. I was struggling to work as the lack of sleep made me feel ill at work and often faint. After 1 month of taking them my panic attacks stopped. And I slept.. I have however reduced them to 7.5 as I had issues waking up in the morning with a bad headache. And feel a lot better now. I am also able to work. So a really good antidepressant for insomnia and panic attacks. However I have put some weight on. But worth it for the positive benefits it gives."

• Natas...
• Taken for 1 to 6 months
• December 29, 2015

"Hi my daughter is 12 I has been taking mirtazine for a good 2 months because she could not sleep and had depression. It is the best for her she can sleep and the depression it is getting better. I hope it keeps working."

• mike
• Taken for 1 to 6 months
• February 28, 2019

"Good for getting you to sleep at 15 mg but the next day horrendous depression, amplified ten times. My aggression increased too. Was on this two months but had no effect on depression, not at all. All that it did the next day was make me want to curl up. Came off of it feel a lot better."

• 170
• Taken for less than 1 month
• April 2, 2019

"I was on a SSRI for 2.5 years to treat depression and anxiety. The SSRI worked for a couple of months until my life took on more responsibility. I started to feel depressed and anxious again. One major side effect of the SSRI was a significant reduction in sex drive. Being a male, that lowered my confidence even more. I've been on mirtazapine for 2 weeks now, still early days. However, since being on it I immediately experienced improvements. My sex drive has returned to normal, I sleep much better, and I am more excited about life in general. The only real side effect I've experienced is dizziness on a daily basis. Hopefully this will go away in a few weeks."

• JWinsy
• July 6, 2016

"Started 7.5 mg of Mirtazapine on June 3rd for anxiety and depression. My episode started in the begging of May and I was having good days and bad days. After starting the mirtazapine, I still feel general sadness and not myself. I had moments of clarity but just wasn't feeling enough affect. After three weeks, I upped my dose to 15 mg. I immediately felt better and like my old self. I was so excited but that only last for a week. The last two days the depression/sadness has crept back in along with the worrying. I called the doc to see about upping my dosage to 30mg. She wants me to give it another week and then go back and talk about upping the dosage or trying a different med. I can't do SSRI's. they sent me off the deep edge."

• Anonymous
• November 24, 2017

"ruined my life. It caused me brain damage, destroyed my family, destroyed me. My life is ruined. My advice is go and take a month off and go travelling. That will help you a lot more. My brain damage makes it hard to write. I have a first class degree and now my brain is reduced to gravy. I say get away from these horrible meds"

• Megat...
• May 2, 2017

"I was put on 15mg of Mirtazapine about a month ago and it was the best decision ever. I've been very depressed and underweight (unintentionally due to stress and high metabolism) almost all my life. I went to my doctor at the end of my rope, having been off any type of anti-depressants, anti-anxiety etc for 5 years - I told him that all the pervious SSRIs and SNRIs I'd been on hadn't worked because they made me both suicidal and lose more weight (I generally have a BMI of 15-17 max). He recommended this and if it weren't for me giving medicinal treatment one more shot, I wouldn't be sleeping, eating or in the process of finally getting my degree and my own place! The only downside was that in the first 2 weeks I had some dry mouth/tiredness."

• Lisar
• Taken for 1 to 6 months
• August 11, 2021

"I was diagnosed bipolar 2 this year, I'm 41 female. What led to my diagnosis was I had become overwhelmingly fatigued and also had panic problems, I felt like I was dying. But the doctors all said it was "just anxiety". What it was was hypomania. The fatigue and all the other body symptoms were from not really sleeping. Once I got diagnosed I took lithium and Remeron. I felt better almost immediately. The Remeron helped me sleep right away at 7.5 my for the first week. I had no side effects. I take 15 my every night and its my 3rd month on it. I get the munchies very badly at bedtime and I have gained weight in the middle. I sleep easily 10 straight hours. But its worth it, I feel, because I am not having major depression, physical symptoms of ptsd or fatigue, and I sleep well. All the terrible symptoms I was experiencing because of fatigue and mania are gone. The Remeron is prescribed to me to help with depressive episodes and also help me sleep when I'm manic. Its done great at both."

• Johnny
• Taken for less than 1 month
• July 9, 2019

"I was diagnosed with major depression and anxiety. It's my first time dealing with meds at the age of 23. I am happy and terrified because my appetite is back tenfold and I am scared that I am going to balloon in my weight. I am taking 15mg mirtazapine once per night for full disclosure to you guys. Before I felt like there was a demon inside me that was causing me to drown in feelings of guilt and awfulness many times a day. This medicine is keeping the demon locked in his cage but some days it feels like nothing is happening at all. I still have an irregular pattern of sleep that will keep me awake in my own mind until 3-6am. My doctor told me that the people around me will notice the effects before I do. Even though my feelings of anxiety are being repressed, I am still biting my nails so hard until they bleed. I don't even realise I'm doing it anymore."

• Blended
• Taken for 1 to 6 months
• May 2, 2016

"Have had a good experience overall with this medication, with an improvement in general symptoms(major depressive disorder). Although I have had nightmares, passing peripheral edema plus unexplained 10 point increase in blood pressure, as side effects. These have been much less and more tolerable than the side effects of the other medications I have used, as listed next. I have also used cymbalta, effexor, allegron and valdoxin (in order of my opinion of there effectiveness) with cymbalta/valdoxin in combination for a period (over 18 months). I have also undergone ECT. If I had this information when I started I would have chosen this medication as a starting point."

• Snax
• November 4, 2019

"I used to have bad panic attacks & found it really hard to sleep before I was prescribed mirtazapine. The first few weeks of getting used to it were awful. I often felt dizzy & nauseated 10 minutes after taking it & collapsed once, luckily a family member was there and I was carried to my bed. After that passed it worked amazingly for me. I haven't had a panic attack since having it & I've found it a lot easier to sleep. I feel more calmer & less paranoid than I used to. I went from a size 4 to a size 8/10 & it's been rough trying to lose the weight. I have only started taking control of it now. It gave me a huge appetite at the beginning & I was constantly hungry. I've also noticed that I'm a lot more tired lately & have a lot less energy than I used to. Sometimes I also find it a little difficult to sleep. Another odd thing I have noticed, I dream almost every night & remember all them. They are usually odd dreams although I've gotten sleep paralysis a few times (have history of them)"

• Anonymous
• Taken for less than 1 month
• December 22, 2015

"Have been on sertraline and citalapram both unsuccessfully in the past, Mirtazapine was a final resort and whilst for the most part my low mood and anxiety has surpassed the side effects of this drug are way too much to handle. I couldn't leave the house for the first three days as the exhaustion was too much I was sleeping twelve hours at night at taking two three hour naps during the day. It has also had a horrible affect on my appetite-I cannot stop eating and have put on a fair amount of weight, but the drowsiness that the drug gives means I struggle to exercise. This and the fact that the drug has given me a peculiar feeling that I'm floating or uneasy on my feet. Several times I have had to grab the wall to steady myself. Not for me!!"

• Wildie
• Taken for 1 to 6 months
• October 26, 2020

"mirtazapine didn't help my MDD much. I've been on seroxat, prozac and about 3 or 4 others over the years. There's always something not right. With these I wanted something for sleep but they just made me drowsy and so hungry so I've put on loads of weight which is really bad for me as I have food related MH issues/Ed. I'm not sure what else to do but no doubt they'll give me something else and the circle goes round again. I have to have other ways to help my issues...if help is the right word."

• Elle
• Taken for 2 to 5 years
• July 24, 2019

"I was put on 30 mg at bedtime for MDD and anxiety disorder. I was so relieved that I could finally relax at night without benzodiazepines but I gained 50 pounds (100 initially but lost 50 due to lowering dosage of another medication and drinking water instead of sweet tea). Now I take 45 mg the maximum dosage, half before bed and half in the middle of the night. I sometimes want to take it for anxiety during the day but I’m already at maximum dosage. I don’t think I’ll ever be able to get off this medication but I really want to lose the extra 50 lbs. It’ is supposedly no addictive but I couldn’t get off of it on my own. I’m definitely dependent on it but it does relieve my anxiety and helps me sleep. You just have to resist the sugar cravings especially at bedtime!"