I'm not supposed to take aspirin or acetemaphen because of Stage 3 kidney disease. I have fibromyalgia and have a lot of pain. Celebrex worked fine when the doctor let me take 200 mg twice a day. Because of scares about celebrex's possible connection to heart trouble, she cut me down to one a day. At this dosage the celebrex isn't working; so, I'm trying to find an alternative.